Overview:
In this project, we selected protein based disease semi-randomly and preformed research on the disease and how it effects a specific protein. Our group was assigned Huntington's disease and created the relevant presentation.
Concepts:
Protein synthesis: The process of transforming DNA into a protein; It has three transitions: transcription, the transition from DNA to mRNA, transcription, the reading of the mRNA by a ribosome and assembling a proper polypeptide chain, and folding, the connection and folding of the polypeptide chains together to form a protein. This was the primary concept when finding the cause of the disease.
Protein misfolding: The malformation of a protein due to an improper amino acid sequence. This leads to an inability of a specific function and leads to the development of a genetic disease, such as Huntington's disease.
DNA: The basic code of life. Formed from nucleic acid and provides the code for all life functions. Errors in the DNA or reading the DNA cause the diseases.
Translation: Anti- codons connect with codon to link amino acids into a polypeptide change.
Transcription: DNA is copied into mRNA. Part of protein synthesis.
Folding: Polypeptide chains form alpha helixes and beta sheets and combine. This combination then folds into a complex 3-D shape based on the amino acid sequence and form a protein. An error in this process causes a faulty protein that doesn't work.
mRNA: RNA that copies DNA and transfers the code for various purposes. In this instance, the coping of DNA for protein synthesis.
tRNA: RNA that transfers things. Important within protein synthesis.
Codon: Sets of three DNA bases that are used for protein synthesis. These are read by the ribosome.
Anti- codon: A part that attaches to the associated with the appropriate codon and adds an appropriate amino acid to the polypeptide chain. This is a step in the protein synthesis.
Ribosome: An organelle that makes polypeptide chains by reading mRNA and channeling anti- codons.
RNA Polymerase- Enzyme that follows strand of DNA
Polypeptide Chain- Chain of amino acids
Protein: The macromolecule primarily used for preforming actions. Produced through protein synthesis and the order of amino acids determine the shape and sequence.
In this project, we selected protein based disease semi-randomly and preformed research on the disease and how it effects a specific protein. Our group was assigned Huntington's disease and created the relevant presentation.
Concepts:
Protein synthesis: The process of transforming DNA into a protein; It has three transitions: transcription, the transition from DNA to mRNA, transcription, the reading of the mRNA by a ribosome and assembling a proper polypeptide chain, and folding, the connection and folding of the polypeptide chains together to form a protein. This was the primary concept when finding the cause of the disease.
Protein misfolding: The malformation of a protein due to an improper amino acid sequence. This leads to an inability of a specific function and leads to the development of a genetic disease, such as Huntington's disease.
DNA: The basic code of life. Formed from nucleic acid and provides the code for all life functions. Errors in the DNA or reading the DNA cause the diseases.
Translation: Anti- codons connect with codon to link amino acids into a polypeptide change.
Transcription: DNA is copied into mRNA. Part of protein synthesis.
Folding: Polypeptide chains form alpha helixes and beta sheets and combine. This combination then folds into a complex 3-D shape based on the amino acid sequence and form a protein. An error in this process causes a faulty protein that doesn't work.
mRNA: RNA that copies DNA and transfers the code for various purposes. In this instance, the coping of DNA for protein synthesis.
tRNA: RNA that transfers things. Important within protein synthesis.
Codon: Sets of three DNA bases that are used for protein synthesis. These are read by the ribosome.
Anti- codon: A part that attaches to the associated with the appropriate codon and adds an appropriate amino acid to the polypeptide chain. This is a step in the protein synthesis.
Ribosome: An organelle that makes polypeptide chains by reading mRNA and channeling anti- codons.
RNA Polymerase- Enzyme that follows strand of DNA
Polypeptide Chain- Chain of amino acids
Protein: The macromolecule primarily used for preforming actions. Produced through protein synthesis and the order of amino acids determine the shape and sequence.
Our Project
Reflection
At the start of the project, each group made a Gantt Chart, a visual representation of what needed to be done and when by, and in my opinion an ironic waste of time for this project. We had to spend precious class time updating the chart, that was time we could have been using for working on the project itself. We checked the chart at the beginning of each workday, but had miscalculated the time that each objective needed to be completed, resulting in working outside of class. In the end, the due date was moved, giving me extra time to finish last-minute editing.
We split the workload unevenly and distributed the objectives of the day poorly throughout the duration of the project. At times, the next step could not be completed without the step before. For example, we could not film scenes without having finished the diagram that were to accompany them in the video. My group collaborated well, as we had worked on the previous project together. We got off task at times as a result of this, also the Gantt chart ate up our time and could do a better job of time management.
We split the workload unevenly and distributed the objectives of the day poorly throughout the duration of the project. At times, the next step could not be completed without the step before. For example, we could not film scenes without having finished the diagram that were to accompany them in the video. My group collaborated well, as we had worked on the previous project together. We got off task at times as a result of this, also the Gantt chart ate up our time and could do a better job of time management.